Giuseppe Balistreri Selected Research

Proteins (Proteins, Gene)

7/2023	Complete Protection from SARS-CoV-2 Lung Infection in Mice Through Combined Intranasal Delivery of PIKfyve Kinase and TMPRSS2 Protease Inhibitors.
10/2022	Nanomolar inhibition of SARS-CoV-2 infection by an unmodified peptide targeting the prehairpin intermediate of the spike protein.
8/2022	Nanomolar inhibition of SARS-CoV-2 infection by an unmodified peptide targeting the pre-hairpin intermediate of the spike protein.
6/2022	SARS-CoV-2 requires acidic pH to infect cells.
10/2021	Synergistic Block of SARS-CoV-2 Infection by Combined Drug Inhibition of the Host Entry Factors PIKfyve Kinase and TMPRSS2 Protease.
8/2021	Synergistic block of SARS-CoV-2 infection by combined drug inhibition of the host entry factors PIKfyve kinase and TMPRSS2 protease.

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Giuseppe Balistreri Research Topics

Disease

10	Infections 02/2024 - 01/2021
8	COVID-19 02/2024 - 08/2021
4	Virus Diseases (Viral Diseases) 02/2024 - 08/2022
2	Alzheimer Disease (Alzheimer's Disease) 02/2024 - 01/2023
1	Cognitive Dysfunction 02/2024
1	Vesicular Stomatitis 07/2023
1	Melanoma (Melanoma, Malignant) 01/2023
1	Enterovirus Infections 01/2023
1	Tauopathies 01/2023

Drug/Important Bio-Agent (IBA)

6	Proteins (Proteins, Gene)FDA Link 07/2023 - 08/2021
5	Phosphotransferases (Kinase)IBA 07/2023 - 08/2021
4	apilimodIBA 07/2023 - 08/2021
4	nafamostatIBA 07/2023 - 08/2021
3	camostatIBA 01/2023 - 08/2021
3	Peptide Hydrolases (Proteases)FDA Link 06/2022 - 08/2021
2	Angiotensin Receptors (Angiotensin II Receptor)IBA 02/2024 - 01/2023
2	EnzymesIBA 02/2024 - 01/2023
2	Viral RNAIBA 12/2023 - 01/2023
2	1-Phosphatidylinositol 4-Kinase (1 Phosphatidylinositol 4 Kinase)IBA 07/2023 - 01/2023
2	Serine Proteases (Serine Protease)IBA 07/2023 - 01/2023
2	Peptides (Polypeptides)IBA 10/2022 - 08/2022
2	SARS-CoV-2 spike proteinIBA 10/2022 - 08/2022
2	CathepsinsIBA 10/2021 - 08/2021
1	Air Pollutants (Pollutants, Air)IBA 02/2024
1	Particulate MatterIBA 02/2024
1	Nucleocapsid ProteinsIBA 12/2023
1	Angiotensin-Converting Enzyme 2IBA 12/2023
1	Neuropilin-1IBA 12/2023
1	Protease Inhibitors (Protease Inhibitor)IBA 07/2023
1	Drug CombinationsIBA 07/2023
1	Blocking AntibodiesIBA 01/2023
1	VemurafenibIBA 01/2023
1	raf KinasesIBA 01/2023
1	Double-Stranded RNA (RNA, Double Stranded)IBA 01/2023
1	Phosphatidylinositols (Phosphatidylinositol)IBA 01/2023
1	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 01/2023
1	Cathepsin LIBA 01/2023
1	Antiviral Agents (Antivirals)IBA 01/2023
1	Glycoproteins (Glycoprotein)IBA 08/2022
1	Capsid Proteins (Capsid Protein)IBA 01/2021

Therapy/Procedure

1	Therapeutics 02/2024